This forms the basis of Tumor Specific Transplantation Antigens ( TSTA ) or Tumor Associated Transplant Antigens ( TATA ).
2.
The findings were that the NK cells are inhibited by a transplantation antigen, the major histocompatibility complex ( MHC ) class I, which prevents NK cells from killing their target cells.
3.
This complex would later become known as one of the Major Histocompatibility Complexes ( MHC ), specifically those termed transplantation antigen, a conclusion which would in time have profound effects on the transplantation process.
4.
Simpson is particularly known for her elucidation of the nature of male-associated minor transplantation antigens, and their roles in the generation of immunological tolerance, graft versus host disease, and transplant rejection.
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